Toxicology Research, 08 May 2018, Issue 3, Page 311 to 540
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX007003

CONTENTS

Review Articles (综述)
1. The impact of nanomaterial characteristics on inhalation toxicity
纳米材料表征对吸入毒性的影响
Frank S. Bierkandt, Lars Leibrock, Sandra Wagener, Peter Laux and Andreas Luch
Toxicol. Res., 2018, 7, 321 DOI:10.1039/C7TX00242D 
2. Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective
对乙酰氨基酚代谢、肝脏毒性、生物标志物及治疗干预的展望
Toby J. Athersuch, Daniel J. Antoine, Alan R. Boobis, Muireann Coen, Ann K. Daly, Lucia Possamai, Jeremy K. Nicholson and Ian D. Wilson
Toxicol. Res., 2018, 7, 347 DOI:10.1039/C7TX00340D
3. Evaluation of the relevance of DILI predictive hypotheses in early drug development: review of in vitro methodologies vs. BDDCS classification
药物早期研发阶段评估药物性肝损伤（DILI）预测假说的准确性：体外实验法与BDDCS分类法的比较
Rosa Chan and Leslie Z. Benet
Toxicol. Res., 2018, 7, 358 DOI:10.1039/C8TX00016F
4. The state of bisphenol research in the lesser developed countries of the EU: a mini-review
欧盟欠发达国家双酚类化合物研究现况的微型综述
Michael Thoene, Liliana Rytel, Natalia Nowicka and Joanna Wojtkiewicz
Toxicol. Res., 2018, 7, 371 DOI:10.1039/C8TX00064F 
5. Anticancer, antimicrobial, and analgesic activities of spider venoms
蜘蛛毒液的抗癌、抗菌及止痛活性
Hassan M. Akef 
Toxicol. Res., 2018, 7, 381 DOI:10.1039/C8TX00022K
Papers (论著)
1. The systemic toxicity of heavy metal mixtures in rats
重金属复合物的大鼠系统毒性
Samuel Selorm Fiati Kenston, Hong Su, Zhou Li, Lu Kong, Yafei Wang, Xin Song, Yuanliang Gu, Tabatha Barber, Joni Aldinger, Qihang Hua, Zhen Li, Min Ding, Jinshun Zhao and Xialu Lin
Toxicol. Res., 2018, 7, 396 DOI:10.1039/C7TX00260B 
2. The effects of di-2-ethylhexyl phthalate on testicular ultrastructure and hormone-regulated gene expression in male rats
邻苯二甲酸二（2-乙基己）酯对雄性大鼠睾丸超微结构和激素调控的基因表达的影响
Xiaoyun Qin, Quan Ma, Jianhui Yuan, Xinnan Hu, Qin Tan, Zena Zhang, Li Wang and Xinyun Xu
Toxicol. Res., 2018, 7, 408 DOI:10.1039/C7TX00257B
3. Upregulated has-miR-4516 as a potential biomarker for early diagnosis of dust-induced pulmonary fibrosis in patients with pneumoconiosis
has-miR-4516上调可作为尘肺病人中粉尘诱导肺纤维化早期诊断的潜在生物标志物
Ruixue Huang, Ting Yu, Ying Li and Jianan Hu
Toxicol. Res., 2018, 7, 415 DOI:10.1039/C8TX00031J
4. In silico identification of protein targets for chemical neurotoxins using ToxCast in vitro data and read-across within the QSAR toolbox
利用ToxCast体外数据库和QSAR toolbox软件识别神经毒性化合物的靶蛋白
Y. G. Chushak, H. W. Shows, J. M. Gearhart and H. A. Pangburn
Toxicol. Res., 2018, 7, 423 DOI:10.1039/C7TX00268H 
5. Evaluation of the toxic potential of arecoline toward the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9
槟榔碱对转基因黑腹果蝇(hsp70-lacZ) Bg9三龄幼虫的毒性作用评价
Barkha Shakya and Yasir Hasan Siddique
Toxicol. Res., 2018, 7, 432 DOI:10.1039/C7TX00305F
6. Individual heavy metal exposure and birth outcomes in Shenqiu county along the Huai River Basin in China
中国淮河流域沈丘县重金属个体暴露与出生结局的关系
Zhiqing Lin, Xi Chen, Zhuge Xi, Shaobin Lin, Xin Sun, Xiao Jiang and Haoyuan Tian
Toxicol. Res., 2018, 7, 444 DOI:10.1039/C8TX00009C
7. Pharmacognostic and pharmacological evaluation of Eulaliopsis binata plant extracts by measuring in vitro/in vivo safety profile and anti-microbial potential
通过体外/体内安全性数据及抗菌活性评估拟金茅植物提取物的生药学和药理学特性
Vinod Kumar, Arun K. Sharma, Satyendra K. Rajput, Mahesh Pal and Neerupma Dhiman
Toxicol. Res., 2018, 7, 454 DOI:10.1039/C8TX00017D s 
8. Amino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway
氨基多环芳烃激活Nrf2/ARE抗氧化防御系统并促进炎症应答：PI3K/Akt通路的调控作用
Meiying Wu, Yuting Jiang, Mingyuan Liu, Yu Shang and Jing An
Toxicol. Res., 2018, 7, 465 DOI:10.1039/C8TX00010G
9. Correlation of the cytotoxic effects of cationic lipids with their headgroups
阳离子脂质headgroups与细胞毒性效应的关系
Shaohui Cui, Yueying Wang, Yan Gong, Xiao Lin, Yinan Zhao, Defu Zhi, Quan Zhou and Shubiao Zhang
Toxicol. Res., 2018, 7, 473 DOI:10.1039/C8TX00005K
10. Beneficial effects of folic acid on the kidneys and testes of adult albino rats after exposure to methomyl
叶酸对灭多威诱导成年大鼠肾脏和睾丸毒性的保护作用
Samar Sakr, Hanan Hassanien, Megan Jean Bester, Sandra Arbi, Azza Sobhy, Heba el Negris and Vanessa Steenkamp
Toxicol. Res., 2018, 7, 480 DOI:10.1039/C7TX00309A
11. Transcriptome profiling of HepG2 cells exposed to the flame retardant 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO)
阻燃剂DOPO染毒HepG2细胞的转录组学特征
Boris V. Krivoshiev, Gerrit T. S. Beemster, Katrien Sprangers, Bart Cuypers, Kris Laukens, Ronny Blust and Steven J. Husson
Toxicol. Res., 2018, 7, 492 DOI:10.1039/C8TX00006A
12. The subchronic exposure to malathion, an organophosphate pesticide, causes lipid peroxidation, oxidative stress, and tissue damage in rats: the protective role of resveratrol
有机磷杀虫剂马拉硫磷亚慢性暴露诱导大鼠脂质过氧化、氧化应激及组织损伤和白藜芦醇的保护作用
Erten Akbel, Damla Arslan-Acaroz, Hasan Huseyin Demirel, Ismail Kucukkurt and Sinan Ince
Toxicol. Res., 2018, 7, 503 DOI:10.1039/C8TX00030A
13. Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes
运用流式细胞术分析靛甙、吲哚酚、靛蓝和靛玉红对大鼠胸腺淋巴细胞的损伤效应
Yurie Funakoshi, Ayako Azuma, Mizuki Ishikawa, Satoru Itsuki, Yasuaki Tamura, Kaori Kanemaru, Shogo Hirai and Yasuo Oyama
Toxicol. Res., 2018, 7, 513 DOI:10.1039/C7TX00244K
14. The role of IP3R-SOCCs in Cr(VI)-induced cytosolic Ca2+ overload and apoptosis in L-02 hepatocytes
IP3R-SOCCs在六价铬诱导L-02肝细胞胞浆钙超载和凋亡中的作用 
Qi Liang, Yujing Zhang, Ming Zeng, Lan Guan, Yuanyuan Xiao and Fang Xiao
Toxicol. Res., 2018, 7, 521 DOI:10.1039/C8TX00029H
15. Plasma metabolic profiling analysis of neurotoxicity induced by oxaliplatin using metabonomics and multivariate data analysis
基于代谢组学和多变量数据分析法研究奥沙利铂诱导神经毒性的血浆代谢谱
Yanyan Xu, Yiwei Zhao, Xuejun Guo, Yubo Li and Yanjun Zhang
Toxicol. Res., 2018, 7, 529 DOI:10.1039/C7TX00345E